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The Biggest Celebrities in the Cannabis Industry

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Cannabis 101
Published On 07-06-2025

The Biggest Celebrities in the Cannabis Industry

In the past, celebrities were known for launching clothing lines or perfumes. But in recent years, a new trend has emerged—one that’s more grassroots, both literally and figuratively. The cannabis industry has become a hotspot for celebrity investment and entrepreneurship. From pre-rolls to edibles and high-end flower strains, famous figures are putting their names and passions into cannabis brands across the United States and beyond. With recreational marijuana now legalized in 19 U.S. states and more considering legalization, the green rush is well underway. Below is a look at some of the biggest names leading the charge.

Justin Bieber – Peaches by Palms

Inspired by his chart-topping single “Peaches,” Justin Bieber launched a cannabis line in collaboration with Palms, a well-known pre-roll brand. The limited-edition line offers premium indoor-grown flower pre-rolls available in California, Nevada, Massachusetts, and Florida. Bieber has been vocal about the stigma around cannabis use, saying in a Vogue interview that while he enjoys marijuana, he's often made to feel guilty for it. With this launch, he aims to normalize its usage and contribute to de-stigmatizing the culture surrounding it.

Seth Rogen – Houseplant

Actor and comedian Seth Rogen, known for his affinity for cannabis, co-founded Houseplant with his longtime collaborator Evan Goldberg. Originally launched in Canada, Houseplant offers thoughtfully curated cannabis strains like Pancake Ice and Pink Moon. In addition to high-quality flower, the brand also sells home goods like ashtrays and ceramics—some even designed by Rogen himself. Houseplant stands out for its attention to both form and function, appealing to cannabis connoisseurs who appreciate style and quality.

Trixie Garcia – Garcia Handpicked

Trixie Garcia, daughter of Grateful Dead frontman Jerry Garcia, launched Garcia Handpicked to celebrate her father’s legacy and provide a socially conscious cannabis brand. With products like pre-rolls, flower, and gummies shaped like guitar picks, the brand targets both Deadheads and modern consumers. Trixie has emphasized the importance of using the brand to right past wrongs, highlighting how many have faced incarceration for cannabis-related offenses while now others profit from it legally.

Jay-Z – Monogram

Music mogul Jay-Z entered the cannabis market with his luxury brand Monogram, launched in partnership with Caliva. Monogram focuses on high-end, hand-rolled cannabis products that reflect craftsmanship and sophistication. With strains like No. 01, No. 88, and No. 96, the brand aims to elevate cannabis to the level of fine wine or premium cigars. Jay-Z has stated that Monogram is about giving cannabis the dignity it deserves while supporting social equity efforts in the industry.

Snoop Dogg – Leafs by Snoop

Snoop Dogg, one of the most iconic cannabis users in pop culture, founded Leafs by Snoop in 2015. The brand features a range of products, including flower strains like Northern Lights and Cali Kush, as well as edibles such as chocolates and gummies. Snoop also co-founded Merry Jane, a digital media platform for cannabis culture. Leafs by Snoop was one of the first major celebrity-backed cannabis brands and remains influential today.

Jim Belushi – Belushi's Farm

Jim Belushi, known for his acting career, transitioned to farming cannabis in Oregon, where he owns a 93-acre estate. Belushi’s Farm produces several product lines, including The Blues Brothers, Chasing Magic, and Good Ugly Weed. He’s also collaborated with chocolate and edibles brands to expand his offerings. For Belushi, growing cannabis has been a personal healing journey as well as a business venture, helping him cope with the loss of his brother, John Belushi.

Tommy Chong – Tommy Chong's CBD

Tommy Chong, a longtime cannabis advocate and half of the comedy duo Cheech & Chong, launched a CBD brand that includes oils, gummies, and nano-CBD products aimed at wellness. The products are made from U.S.-grown hemp and use advanced nanotechnology for faster absorption. Chong continues to champion cannabis for both medical and recreational use, bridging the gap between legacy users and modern health-conscious consumers.

Wiz Khalifa – Khalifa Kush Enterprises

Rapper Wiz Khalifa launched Khalifa Kush, a brand offering high-THC strains and cannabis oils developed to match his personal preferences. Initially reserved for his private stash, the Khalifa Kush strain is now available to the public in select dispensaries across North America. The brand promotes premium quality and targets those looking for strong, flavorful cannabis products.

The Game – Trees By Game

West Coast rapper The Game created Trees By Game in 2016 to bring his own curated cannabis strains to the market. The brand offers flower and pre-rolls, with a focus on quality and freshness. The Game hopes to turn Trees By Game into a globally recognized cannabis brand and has formed partnerships with large cannabis companies to scale distribution.

Mickey Hart – Mind Your Head

Grateful Dead drummer Mickey Hart entered the cannabis space with Mind Your Head, a brand designed for creative exploration and mindfulness. His pre-rolls, made from Chemdog flower, are sold in collectible tins and reflect his love of psychedelic experiences and spiritual wellness. Hart views cannabis as a tool for enhancing curiosity and imagination.

Lil Wayne – GKUA Ultra Premium

Launched in 2019, GKUA Ultra Premium is Lil Wayne’s cannabis brand offering high-THC products including flower, concentrates, and vapes. GKUA is marketed as delivering the “best high of your life,” with premium strains selected by expert growers. The brand has expanded into multiple states and emphasizes both potency and luxury.

Shavo Odadjian – 22Red

System of a Down bassist Shavo Odadjian founded 22Red, a lifestyle brand offering cannabis, fashion, and music-inspired products. The name reflects his personal attachment to the number 22. With products in California, Arizona, and Nevada, 22Red includes flower, pre-rolls, and branded merchandise designed to appeal to both cannabis users and creative minds.

Al Harrington – Viola

Former NBA star Al Harrington founded Viola in honor of his grandmother, who used cannabis for glaucoma. Viola not only produces high-quality cannabis but also leads initiatives to support communities affected by the war on drugs. Through the Viola Cares initiative, Harrington is working to create opportunities for people of color in the cannabis space.

Method Man – TICAL Official

Named after his solo debut album, Method Man’s TICAL brand aims to bring quality cannabis products to communities of color. Starting with four strains—Cake, Gelato, OG, and Punch—TICAL focuses on partnerships with Black-owned dispensaries and aims to create opportunities for those disproportionately impacted by cannabis criminalization.

Juicy J – Asterisk*

Juicy J joined forces with Gary Vaynerchuk to launch Asterisk*, offering strains like Wildflower and Mystic Potion. The brand is expanding to include apparel and music production tools. Juicy J views cannabis as a cultural movement and is enthusiastic about the brand’s growth beyond California.

Jaleel White – itsPurpl

Known for playing Steve Urkel on "Family Matters," Jaleel White created itsPurpl in partnership with 710 Labs. Specializing in Purple Urkle genetics, the brand includes flower, vapes, and unique products like the “Noodle Doink”—a joint rolled with a fusilli noodle as a crutch. White wants to promote diversity in cannabis ownership and leadership.

Melissa Etheridge – Etheridge Botanicals

After using cannabis during her breast cancer treatment, Melissa Etheridge became a strong advocate. Her brand, Etheridge Botanicals, offers flower strains categorized by time of day (Morning, Noon, and Night), all sold in eco-friendly packaging. The company also supports social justice causes like the Last Prisoner Project.

Jason Gann – Wilfred CBD & Hemp

Australian actor Jason Gann, creator of the TV series "Wilfred," founded his own CBD brand after the show ended. Wilfred CBD & Hemp sells affordable pre-rolls in indica, sativa, and hybrid strains. Gann manages all aspects of the company himself, from marketing to licensing, with a focus on accessibility and quality.

Carlos Santana – Mirayo by Santana

Legendary musician Carlos Santana created Mirayo to reflect his Latin heritage and spiritual beliefs. The brand features sun-grown cannabis strains named Radiance, Symmetry, and Centered, and a CBD-rich line called Essence. Santana views cannabis as a sacred plant that enhances meditation and creativity.

Willie Nelson – Willie’s Reserve

A longtime cannabis advocate, Willie Nelson launched Willie’s Reserve in 2016. The brand sources cannabis from independent farmers in legal states and offers flower, pre-rolls, and vape products. Willie’s Reserve promotes sustainability and local partnerships, while honoring Nelson’s legacy of activism and music.

B-Real – Dr. Greenthumb’s

B-Real, frontman of Cypress Hill, owns Dr. Greenthumb’s, a chain of dispensaries offering top-shelf cannabis and branded merchandise. With multiple locations in California and one in Oklahoma, the brand is known for its expert cultivation and community-driven approach. B-Real aims to educate and empower cannabis consumers nationwide.

Bob Marley – Marley Natural

Created by the Marley family in partnership with Privateer Holdings, Marley Natural is the first global cannabis brand. Offering premium flower, oils, and topicals, the brand celebrates Bob Marley’s legacy and his belief in cannabis as a tool for peace and healing. Their products also support social justice programs through the Marley Natural Foundation.

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